Niacin alleviates dairy cow mastitis by regulating the GPR109A/AMPK/NRF2 signaling pathway

W Guo, J Liu, W Li, H Ma, Q Gong, X Kan… - International Journal of …, 2020 - mdpi.com
Mastitis is one of three bovine diseases recognized as a cause of substantial economic
losses every year throughout the world. Niacin is an important feed additive that is used
extensively for dairy cow nutrition. However, the mechanism by which niacin acts on mastitis
is not clear. The aim of this study is to investigate the mechanism of niacin in alleviating the
inflammatory response of mammary epithelial cells and in anti-mastitis. Mammary glands,
milk, and blood samples were collected from mastitis cows not treated with niacin (n= 3) and …
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